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This entails problems in terms of potential side effects for antioxidant therapy, which have been largely ignored in most clinical use of antioxidants

Single-cell transcriptomic profiling has revealed marked heterogeneity among alveolar fibroblast subpopulations, including age-dependent subsets with distinct sensitivity to oxidative stress and ferroptotic signals (125)

A subset of these triple negative tumors reportedly co-express the Np63 isoform exclusively with TAp73